Causes Of The Directivity Of The Insulator Effect

Since some enhancers are located upstream of the promoter and some are located downstream, the effect of dead end insulators does not depend on the relative position of dead end suspension insulators to the promoter. Therefore, the reason for the directionality of the effect of polymer deadend insulator has not been truly clarified. At present, two loci have been found to affect the function of porcelain dead end insulators in a trans-activating manner. The nuclear protein encoded by gene S2J (Hw) recognizes suspension insulator and suspension composite insulator and has an insulating effect only after binding to it.